Membranous Nephropathy

Also called: Membranous Glomerulonephritis, Membranous Kidney Disease

Our approach

In Long Hai Kidney Disease Hospital, one of the world's largest kidney disease specialized hospital focus extraordinary expertise on each patients. Your treatment and care are carefully planned to address your needs and to ensure you receive the most advanced treatment with no side effects.

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Our hospital is known nationwide as one of the leading centers for Membranous Nephropathy treatment. We have the most developed approaches that have enable thousands of patients with this disorder enjoy a normal life once again.

We take a team approach to Membranous Nephropathy treatment, providing comprehensive, yet highly specialized, treatment.

Groundbreaking Research

As the largest kidney disease specialized hospital, Long Hai Kidney Disease Hospital is a leading institute for looking into new methods of kidney disease diagnosis and treatment. You benefit from the most advanced research and get recovered more quickly.

Membranous Nephropathy Facts

Membranous Nephropathy is idiopathic in the majority of cases; about 25% of adults and 80% of children have an identifiable immunological stimulus (secondary Membranous Nephropathy). The peak incidence is between 30~50 years old, and it is particularly prone to patients over 50 years of age who have Nephrotic Syndrome.

Membranous Nephropathy, also known as Membranous Glomerulonephritis, describes a disorder in which the small blood vessels in the kidney (glomeruli) become inflamed and thicken. About 40% of patients may ultimately develop to Renal Failure.

If you have been diagnosed with Membranous Nephropathy, we’re here to help. Call +86-18395615012 to make an appointment or request an appointment online.

Since early diagnosis improves your chances for successful treatment, it's important for renal lesions to be found as soon as possible. Long Hai Kidney Disease Hospital uses the most advanced techniques and technology to guarantee an accurate diagnosis of Membranous Nepropathy.

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Your doctor will ask about your symptoms and medical history, and perform a physical exam. A physical exam may show swelling, or edema.

Membranous Nepropathy Tests

A urinalysis may reveal proteinuria (protein in urine) or hematuria (blood in urine). GFR, or Glomerular Filtration Rate, is usually nearly normal. Other tests can be done to see how well the kidneys are working. These tests are:
BUN (blood urea nitrogen)
Serum creatinine
Creatinine clearance
An antinuclear antibody test for collagen vascular disease
Screening blood tests for autoimmune diseases
Tests for hepatitis B and C
Ultrasound or CT scans to examine the structure of your kidneys and urinary tract

Plasma albumin levels may be low, but levels of cholesterol and triglyceride may be high.

Kidney biopsy confirms the diagnosis of Membranous Nephropathy.

If you have been diagnosed with Membranous Nephropathy, we’re here to help. Call +86-18395615012 to make an appointment or request an appointment online.

Membranous Nephropathy is caused due to thickening of part of the glomerular basement membrane, which is a part of the kidneys that helps filter wastes and extra fluid from the bloodstream. It is one of the most common cause of Nephrotic Syndrome.

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The condition may be primary kidney disease of uncertain origin, or it can be caused by other conditions.

Risk factors for Membranous Nephropahty include:
▪ Infections, such as hepatitis B, malaria, syphilis, and endocarditis
▪ Use of certain medications
▪ Exposure to toxins like gold and mercury
▪ Autoimmune disorders, such as systemic lupus erythematosus, rheumatoid arthritis
▪ Blood cancers, such as leukemia and non-Hodgkin lymphoma
▪ Melanoma, a kind of skin cancer

This disease occurs in about 2 out of 10,000 people. It may occur at any age but is more common after age 40.

If you have been diagnosed with Membranous Nephropathy, we’re here to help. Call+86-18395615012 to make an appointment or request an appointment online.

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Symptoms of Membranous Nephropathy often begin slowly over time, and may include:
● Swelling, or edema in any part of the body
● Foamy, or frothy urine
● Weight gain
● Loss of appetite
● Urination, excessive at night
● Hypertension, or high blood pressure
● Fatigue.

If you have been diagnosed with Membranous Nephropathy, we’re here to help. Call +86-18395615012 to make an appointment or request an appointment online.

Long Hai Kidney Disease Hospital has led the way to new methods to treat Membranous Nephropathy. We tailor your care to include advanced therapies that give you highest chance for successful treatment with no side effects.

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We adopt immunotherapy to treat immune-mediated kidney disease including Membranous Nephropathy. It is a comprehensive treatment with the treating process of blocking the undue inflammatory response, clearing up the immune complex, protecting the healthy renal cells and tissues, recovering the impaired kidney function and regulating the immune system.

In immunotherapy, we firstly utilize the newest immunosuppressive drugs to restrain the immoderate inflammatory response.

Then the herbal remedy, called Micro-Chinese Medicine Osmotherapy is applied to help us clear the immune complex. Meanwhile, the overall immunity can be improved.

To restore the renal function, the most advanced Stem Cell Therapy is adopted. Stem cells can differentiate into desired healthy renal cells to replace the necrotic ones. Finally, immune clearance can help us clear the immune complex completely.

In this way, the renal function is restored and the immune system get regulated. Membranous Nephropathy is treated from the root cause.

If you have been diagnosed with Membranous Nephropathy, we’re here to help. Call +86-18395615012 to make an appointment or request an appointment online.

A proper diet is important for you which can guarantee a better recovery, so it is worthful and rewarding to carefully arrange an reasonable diet.

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Consume high-quality protein.
Ensure enough high-quality protein. The amount should be proper in order to relieve the burden of the damaged kidneys. The intake can be 1~1.2g/kg (weight). Foods that contain high-quality protein include fresh milk, eggs, lean meat, etc.

Increase the amount of energy intake.
Lack of caloric intake may cause increased wastes containing nitrogen, so you need to eat high energy food while low-protein, such as low-protein starch, sugar and vegetable oil. The amount of caloric can be 30~40 kilo calorie (weight).

Limit the water intake.
Daily amount of water intake equals the urine output yesterday and 500~700ml. For example, if the urine volume yesterday is 500ml, then 500+ 500 to 700ml=1000~1200ml.

Restrict the amount of salt.
Proper amount of daily salt intake should be controlled within 5g. Too much consume of salt can result in edema or aggravate the high blood pressure.

If you have been diagnosed with Membranous Nephropathy, we’re here to help. Call +86-18395615012 to make an appointment or request an appointment online.

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Factors that can increase your risk of Membranous Nephropathy include:

Medical conditions can damage your kidneys.
Certain diseases and conditions increase your risk of developing Membranous Nephropathy, such as lupus and other autoimmune diseases.

Medications
Medications that can cause Membranous Nephropathy include nonsteroidal anti-inflammatory drugs and gold salts.

Infections
Examples of infections that increase the risk of Membranous Nephropathy include hepatitis B, hepatitis C and malaria.

The following steps may help reduce your chances of getting MN:
Firstly, ensure that you have enough rest and avoid over-strain work or infection.
Secondly, arrange a low-protein diet and supplement of vitamin.
Finally, avoid using certain medicines that may cause damage to your kidneys.

If you have been diagnosed with Membranous Nephropathy, we’re here to help. Call +86-18395615012 to make an appointment or request an appointment online.

The natural history of Membranous Nephropathy varies from patient to patient. Approximately 30% of individuals will have spontaneous remission. Research shows that the overall survival rate in 10 years is about 83%. Most patients with slight or moderate proteinuria have a benign course of disease. Those who have less than 3.5g/day proteinuria or whose kidney function is normal within 3 years before the onset of the disease have a good prognosis.

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Membranous Nephropathy in women, children and the young as well as secondary (drug-induced) MN patients have good prognosis. Indications of a poor prognosis include:
▪ Massive protein in the urine (>10g/day)
▪ Severe high blood pressure
▪ Early presence of decreased GFR
▪ Advanced CKD stages (Stage III or IV)
▪ Atrophy of the tubules and interstitial fibrosis.

If you have been diagnosed with Membranous Nephropathy, we’re here to help. Call +86-18395615012 to make an appointment or request an appointment online.