How to Know Your Kidney Function Is Failing

How to Know Your Kidney Function Is FailingTo determine whether a person’s kidney function is normal, it must be to have certain standards and parameters for reference. So how do you know whether our renal function is normal? In the following we will give you some reference.

Blood pressure (BP):

Hypertension is one of the leading causes of kidney disease. Mild hypertension is harmless, but serious long-term high blood pressure can damage arteries and cause heart failure, cerebral edema and cerebral hemorrhage. A lot of antihypertensive drugs for high blood pressure are effective. A low salt diet for more than 10% of hypertensive patients is effective. High blood pressure caused by overweight should be losing weight.

Serum creatinine (Scr):

The clinical detection of serum creatinine is a common and main method of renal function.

What is creatinine on earth?

The endogenous creatinine is a product of the metabolism of human body muscle. Creatinine is a small molecular substance, which can be filtered through the glomerulus, rarely absorption in the malpighian tube, and daily of creatinine in the body almost all discharged through urine. So it is generally not affected by the amount of urine. When kidney function insufficiency, creatinine will accumulate in the body becoming harmful substances to human body. Generally speaking, normal range of serum creatinine upper limit is 100 umol/l.

Serum creatinine and urea nitrogen at the same time test is more meaningful and precise. If both of them increase at the same time, it tells that your kidney function has been badly damaged.

Renal insufficiency according to serum creatinine values can be divided into four periods:

First stage, renal insufficiency compensatory period: serum creatinine (Scr) 133 ~ 177 umol/L.

Because renal compensatory ability is strong, the clinical renal function is declined to some extent, but its ability of excretion metabolites and regulates water and electrolyte balance can still meet the normal needs. Therefore, no symptoms appear in clinical, renal function tests are also in the normal range, or occasionally slightly higher.

Second stage, renal insufficiency decompensated period: serum creatinine (Scr) 177 ~ 443 umol/L.

Fibrosis and glomerular sclerosis injury about 60% - 75%, kidney has certain obstacles when it excretes wastes. High creatinine and blood urea nitrogen levels are higher or above normal. The symptoms of anemia, fatigue weakness, weight loss, not easy to concentrate, etc. appear, but patients often ignore.

Third stage, renal failure stage: serum creatinine (Scr) 443-707 umol/L.

Glomerular sclerosis, renal tubular fibrosis and renal vascular fibrosis lead to severe kidney damage. Anemia obvious, urine output at night increased, and serum creatinine and blood urea nitrogen increased obviously with acidosis. If patients do not take systemic treatment, the condition will develop to ESRD so that treatment is more difficult.

The last stage, uremia: serum creatinine (Scr) > 707 umoll/L.

Glomerular damage is more than 95% with serious clinical symptoms, such as severe nausea, vomiting, less urine, swelling, malignant hypertension, severe anemia, itchy skin, etc.

Therefore, once you have some of the above symptoms, please check up to confirm. Welcome to contact online doctor or leave message below.

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